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Image Search Results
Journal: International Journal of Endocrinology
Article Title: CS27109, A Selective Thyroid Hormone Receptor- β Agonist Alleviates Metabolic-Associated Fatty Liver Disease in Murine Models
doi: 10.1155/2023/4950597
Figure Lengend Snippet: Chemical structure, THR- β activity, and PK properties of CS27109: (a) chemical structure of several oral and liver-targeted THR- β agonists, including KB-141, VK2809, MGL3196, and CS27109, (b) THR- α and THR- β activity for each compound were determined by a luciferase reporter gene assay, (c) hERG test of CS27109 was conducted by the QPatch HTX, (d) mouse, and (e) rat PK studies for CS27109 and MGL3196.
Article Snippet: hERG test was performed by
Techniques: Activity Assay, Luciferase, Reporter Gene Assay